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Join us for the 5th Annual Symposium on Multiscale Cell Fate October 24 – 25, 2022

The NSF-Simons Center for Mulitscale Cell Fate Research (CMCF) is pleased to announce that its 2022 Annual Symposium will be held on October 24 – 25, 2022, at the Beckman Center of the National Academies of Sciences and Engineering located at UC Irvine.

This Symposium will focus on emergent properties of cell fate and provide several opportunities for initiating collaborations between young researchers across disciplines, including a competition for the Interdisciplinary Opportunity Award program to support collaborative projects.

The symposium invites submission of abstracts for posters or/and contributed talks.

Register here to attend the symposium in-person

The price for registration is $120USD.

Students are eligible for registration discount. Please use Stdt50 for ID code when you register to get 50% off on your registration fee.

Effective October 4, 2021, the National Academies requires that all visitors to The Beckman Center be fully vaccinated against COVID-19. Visitors must show their official COVID-19 Vaccination Record Card (or a digital photo of the card) before entering the building. Masks are currently optional for those that are up-to-date on their vaccinations. Up-to-date means a person has received all recommended doses in their primary series of COVID-19 vaccine, and booster when eligible. The National Academies are encouraging, not mandating, visitors who are not up-to-date with their vaccination to wear a mask while indoors, with the exception of when one is actively eating and/or drinking.

Current confirmed speakers:

Greg Barsh, HudsonAlpha Institute For Biotechnology




Oliver Bell, University of Southern California




Michelle Digman, University of California, Irvine




Allon Klein, Harvard University




Denise Kirschner, University of Michigan




Jingyi Jessica Li, University of California, Los Angeles




Wallace Marshall, University of California, San Francisco




Yanlan Mao, University College London




Padmini Rangamani, University of California, San Diego




Santiago Schnell, FRSC, University of Notre Dame




Suzanne Sindi, University of California, Merced




Feng Yue, Northwestern University




Elazar Zelzer, Weizmann Institute of Science

Click to view the 2022 Symposium Program

Day 1 – Monday, October 24, 2022

07:45 – 08:25

Registration & Breakfast

08:25 – 08:30

Opening Address

Session 1 – Session Chair: Arthur Lander

08:30 – 09:05

Subcellular Cell Fate, Wallace Marshall

09:05 – 09:40

Metabolic Profiling and Tracking Phenotypic Changes in Mitochondria in Cancer Cells with Mitometer and the Phasor Approach to FLIM, Michelle Digman

09:40 – 09:45

IOA Announcement (Arthur Lander)

09:45 – 10:00

Coffee Break

Session 2 – Session Chair: Thomas Schilling

10:00 – 10:35

Stochasticity and dynamics of cell differentiation, Allon Klein

10:35 – 11:10

Revisiting the Model of Limb Skeleton Development, Elazar Zelzer

11:10 – 11:45

Coping with Mechanical Stress: Tissue Dynamics During Development, Homeostasis and Repair, Yanlan Mao

11:45 – 01:15


Session 3 – Session Chair: Jin Yu

01:15 – 01:50

Multi-Scale Modeling Can Predict Factors Driving the Immune Response and Treatment in Tuberculosis, Denise Kirschner

01:50 – 02:25

Multiscale Modeling of Membrane-Actin and Actin-Cross Linker Interactions, Padmini Rangamani

02:25 – 03:00

Coffee Break

Session 4 – Session Chair: Jun Allard

03:00 – 05:00

IOA and Contributed Short Talks


03:00 – 03:10  Michael Norton, Rochester Institute of Technology

03:15 – 03:25  Lorenzo Scipioni, UCI IOA Team

03:30 – 03:40  Axel Almet & Renzi Hou, UCI IOA Team

03:45 – 03:55  Jinghao Chen & Jesse Holt, UCI IOA Team


04:00 – 04:10  Francesco Palomba & Giulia Tedeschi, UCI IOA Team

04:15 – 04:25  Jinsu Kim, POSTECH

04:30 – 04:40  Ethan Hollingsworth, UCI

04:45 – 04:55  Kwadwo Bonsu, UCI

05:00 – 06:00

Reception and Poster Session

06:00 – 08:00


Day 2 – Tuesday, October, 25, 2022

08:00 – 08:30


Session 1 – Session Chair: Xing Dai

08:30 – 09:05

Developmental Mechanisms of Self-Organizing Color Patterns in Cats, Greg Barsh

09:05 – 09:40

Is the Publicly Available Data of Physical-Chemistry Constants Reliable to Build Multiscale Models in Biology? Santiago Schnell

09:40 – 10:00

Coffee Break and Poster Session

Session 2 – Session Jing Zhang

10:00 – 10:35

Structural Variants, Epigenome and 3D Genome Structure in Cancer, Feng Yue

10:35 – 11:10

ZFP462 Targets Heterochromatin to Safeguard Neural Lineage Specification, Oliver Bell

11:10 – 11:45

Enhancing Rigor and Reliability of Single-Cell Data Science, Jingyi Jessica Li

11:45 – 01:15


Session 3 – Session Chair: German Enciso

01:15 – 01:50

TBA, Suzanne Sindi

Session 4 – Session Chair: Christopher Miles

01:50 – 04:00

IOA and Contributed Short Talks


01:50 – 02:00  Amanda Alexander, University of Houston

02:05 – 02:15  Ali Khalilimeybodi, UC San Diego

02:20 – 02:30  Ke Xu, UCI

02:35 – 02:45  Lingxia Qiao, UC San Diego


02:50 – 03:00  Sophia Hu, University of Pittsburgh

03:05 – 03:15  Guanao Yan, UC Los Angeles

03:20 – 03:30  Ping Wu, University of Southern California

03:35 – 03:45  Stephenson Chea, Jesse Krege, Ivy Xiong & Xiaojun Wu, UCI/USC IOA Team

03:50 – 04:00  Minh Vu & Christian Guerrero-Juarez, UCR/UCI IOA Team

04:10 – 04:15

Abstract Due and Adjourn

Research at the interface is most powerful when it is driven by collaborations of young researchers given sufficient resources and a fast timeline. We therefore present the Interdisciplinary Opportunity Award program for new, short-term (one-year) collaborative projects driven by trainees (graduate students, postdoctoral researchers, not PIs).

At the Annual Center Symposium, a topic will be announced. Self-selected teams of interested junior researchers need to produce short abstract-like proposals by the end of the Symposium. The teams must be comprised of members from at least two cross-disciplinary labs (from either mathematical sciences or experimental labs), with at least one group of each team from UCI. A preliminary proposal is due by the end of the Symposium. Full proposals (<3pages) must be submitted within two weeks, which will then be evaluated quickly (~2 weeks) by a Center committee. The winning teams will receive $10,000 to support the collaborative project over one year, and  will attend the Center Early-Career Researcher Symposium and next year’s Annual Symposium on Multiscale Cell Fate, scheduled for April 2023 and October 2023 respectively, to present their results. Winning proposals are selected for their ambition, their feasibility (within a year), and their potential to lead to lasting long-term collaborations.

  • The 2022 CMCF Annual Symposium IOA theme is Space and Time:  The proposal must link spatial and temporal scales.  Spatial may refer here to physical space, or location in a virtual space such as a parameter space, gene expression space, or graph. “.
  • Form a self-selected team with other early-career researchers (graduate students, postdocs, undergraduate students). The teams must include members from at least two labs, who are on different sides of the mathematical and experimental spectrum (very broadly interpreted), and at least one member from UCI.
  • A short abstract-like pre-proposal is due by the end of the Symposium on Tuesday, October 25th, 2022 at 4:30pm. It should be e-mailed to with subject “2022 IOA” and must include the following information:
    1. Team member names and affiliations,
    2. PI names and affiliations,
    3. Project title,
    4. Brief project description
  • Full proposals (<3pages) must be submitted by November 15, 2022 (see details below), and will then be carefully evaluated.
  • PIs must send an e-mail acknowledging support before winning teams are awarded.
  • The winning teams will be informed by the end of November via email.
  • Winning teams will receive a budget of $10,000 for research expenses to support the collaborative project over one year. For example, this may include travel between the collaborating institutions, or experimental consumables. Some restrictions apply; please contact for more information.
  • The funds must be expended within the year. We emphasize fast project result generation!
  • The winning teams are required to:
    1. present a “work-in-progress” talk at the Center’s Early-Career Researcher Symposium, scheduled for April 2023. At least one team member must therefore attend, although all team members are encouraged to do so. And,
    2. all team members must attend and present their final results at the next year’s Annual Symposium on Multiscale Cell Fate, tentatively scheduled for October 2023.

After submitting a pre-proposal, the next step is the submission of the full 3-page proposal. This proposal should include:

  • Names of participants, their career stage (grad student, postdoc, etc), their institutional affiliations, and their PI names,
  • The project title, which matches the title from the pre-proposal,
  • A project description including its significance.

A rough budget is not required in the proposal, but you are welcome to include one if you wish.

Separately, the PIs involved (thesis advisors for PhD students) must send an e-mail acknowledging their support for the proposal. This can be very brief (for example, “I support STUDENT NAME’s IOA proposal.”). If the PI is committing resources, e.g., lab equipment or computing cluster time, this should be mentioned in their e-mail of support too.

These items should be e-mailed to with subject “2022 IOA.”

The deadline for the full proposal is Tuesday, November 15th at midnight. Winners will be informed by November 30th.


John Wayne Airport (SNA)
John Wayne Airport is located just 4 miles from UC Irvine. Most major carriers service this airport.
Long Beach Airport (LGB)
Long Beach Regional Airport is located approximately 25 miles from UC Irvine. Jet Blue Airlines and Southwest Airlines are the primary carriers who service LGB.
Los Angeles International Airport (LAX)
Los Angeles International Airport is So. California’s major hub which serves as the international airport of choice. LAX is located approx. 40 miles from UC Irvine. All major carriers service this airport.

Ayres Hotel and Suites – Costa Mesa

UCI 2022 Rate: $119 for Deluxe Guestroom (single/double occupancy).   Reservations can be made online here.

  • Complimentary Wireless Internet Access in guestroom & public areas
  • Complimentary Freshly baked cookies in the lobby each evening
  • Complimentary self-parking
  • Complimentary shuttle to/from John Wayne Airport and UCI (subject to availability)

Sonesta Irvine – Orange County Airport

17941 Von Karman Ave, Irvine, CA 92614
949-863-1999 (Fax: 949-471-1254)

UCI 2022 Rate: $145 (Sunday-Thursday nights), $115 (Friday & Saturday nights, breakfast not included)   

Sonesta Irvine -University of California-booking link

Rate includes the following:

  • Complimentary Daily Breakfast buffet for one per day (valid only on Monday-Friday mornings)
  • Complimentary Wireless Internet
  • Complimentary Self-Parking
  • Complimentary Shuttle to/from John Wayne Airport
  • Distance from UCI – 3 miles

Sonesta Simply Suites Orange County – Spectrum Center

16150 Sand Canyon Ave; Irvine, CA 92618
949-788-0500 (Fax: 949-788-0566)

Karen Egan, Director of Sales

UCI 2022 Rate: Studio Suite: $115; One Bedroom Suite: $139 (additional discounts for 7 or more nights).  

  • Complimentary high speed wireless internet
  • Complimentary laundry facilities
  • Complimentary fitness center on property
  • Complimentary parking
  • Fully equipped kitchens
  • Weekly housekeeping service
  • 6PM Day of Arrival cancellation policy

SpringHill Suites – by Marriott Irvine, John Wayne Airport

17601 Fitch, Irvine, CA 92614
949-757-0500 (Fax: 949-757-0535)

Alane Millar, Director of Sales
(949) 757-0500

UCI Rate: Rates vary based upon availability. Use Corporate/Promotional Code:  UC0

  • 3.5 Miles from UCI
  • Rate includes breakfast
  • wireless and wired internet included in rate
  • Self Parking included in rate
  • Rate is Last Room Availability

Renaissance Newport Beach Hotel by Marriott

AAA Four-Diamond Award
4500 MacArthur Blvd., Newport Beach, CA  92660
949-476-2001 or Reservations 1.800.468.3571

Lifestyle Hotel completing a $32 Million Refresh in 2018
Located 2 Miles from Orange County Airport (SNA) with Courtesy Transportation
Located 2 Miles from UC Irvine
Rooftop Pool with Fire Pit
Wifi – Offering 500MB Download & 500MB Upload circuit for Guest network
Food & Beverage: Current Coastal Cuisine, In-Room Dining, Market Place or Seasonal Poolside Dining
Fitness Suite and Tennis Courts

Book your corporate rate for  University of California 

Email special requests to: 

Travel awards are offered to help offset the costs of attending the meeting.


  1. Graduate students who are currently enrolled full-time for a post-graduate degree – M.S. or Ph.D., or
  2. Postdoctoral researchers.

Email the following materials to CMCF by September 15, 2022:

  1. Use “2022 Symposium Travel Award” for email subject
  2. Name
  3. Affiliation
  4. A brief statement describing why you are applying for a travel award
  5. Nomination letter – may be written by a professor, advisor, mentor, employer, or director of the department.
The awardees are determined after review of application materials. Priority is given to support gender diversity, under-represented minority groups, or those with disabilities. Awardees will be notified of further rules, such as airline restrictions, upon offer of award.